type I and III IFNs
[대역어] None
[용어속성] Molecule
[용어속성] Molecule
Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection
차등 혈장 세포질 수지상 세포 표현형 및 무증상 및 심한 COVID-19 감염에서 I 형 인터페론 반응
Research Article
[키워드] absence
accompanied
adaptive immune responses
Anti-viral
anti-viral IFN
anti-viral response
antiviral responses
Asymptomatic
asymptomatic SARS-CoV-2 infected subjects
Cell
cells
cellular
characterized
chemokine
chemokines
circulating
contribute
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 pathogenesis
COVID-19 patient
Critically ill
Critically ill patient
critically ill patients
cytokine
Cytokine storm
Cytokines
death
Defense
dendritic cell
dendritic cells
disease severity
early phase
elevated
ENhance
epithelial cells
event
Evidence
Ex vivo
expression
fine-tune
Frequency
hospitalized patient
hospitalized patients
Host
host defense
Host-directed therapies
host-directed therapy
human peripheral blood mononuclear cell
IFN
IFN-stimulated gene
Immune cell
immune cells
immune responses
Immunity
IMPROVE
in vitro
induce
Infection
Inflammatory cytokine
Inflammatory cytokines
inflammatory phenotype
inhibiting viral replication
Innate
innate immune response
Innate immunity
Interaction
interferon
interferons
investigated
low frequency
Lung epithelial cells
mechanism
mononuclear cell
multi-organ failure
neuropilin
observation
Pathogenesis
PBMC
PD-L1 marker
pDC/type I IFN axis
Peripheral blood
pharmacological strategy
phenotype
plasmacytoid dendritic cell
plasmacytoid dendritic cells
pro-inflammatory cytokine
pro-inflammatory cytokines
producing
productive viral replication
progression
protective role
regulate
Regulation
released
responsible
resulting
SARS-CoV-2
SARS-CoV-2 infected subject
SARS-COV-2 infection
SARS-CoV-2 pandemic
secreted
secretion
serum
severe COVID-19
Severe COVID-19 Infection
severe COVID-19 patients
stratified
the cytokine storm
the interferon
tissue damage
TLR7/8
type I
type I and III IFNs
type I and III interferons
Type I IFN
type I IFN producing cells
Viral
viral replication
Viral resistance
virus
viruses
[DOI] 10.1371/journal.ppat.1009878 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1009878 PMC 바로가기 [Article Type] Research Article
The RNA sensor MDA5 detects SARS-CoV-2 infection
RNA 센서 MDA5는 SARS-CoV-2 감염을 감지합니다
Article
[키워드] Calu
Calu-3
cause
Cell
cell line
cellular
contribute
COVID-19
cytokine
Cytokines
cytosolic
detect
Factor
Human
human cells
IFN
IFNs
IL6
independent
independent of
Infection
inhibited
interferons
interferons (IFNs
IRF3
limit
lung cancer
MAVS
MDA5
Pattern recognition receptors
producing
proinflammatory
required
respond
RNA
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 replication
severe COVID-19
TNF
Type
type I
type I and III IFNs
type I and III interferons
Viral host response
viral infection
virus
[DOI] 10.1038/s41598-021-92940-3 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-021-92940-3 PMC 바로가기 [Article Type] Article
Type I and III interferon responses in SARS-CoV-2 infection
SARS-CoV-2 감염에서 I형 및 III형 인터페론 반응
Review
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
antiviral activity
Antiviral effect
antiviral effects
block
caused
cellular response
Cellular responses
contribute
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
Critically ill
critically ill patients
Cytokines
Defense
element
elements
evade
exacerbate
explain
expression
Extensive
Host
host protein
host proteins
hyper-inflammation
IFN
IFN pathways
IFNs
immune cells
immune system
Immune system dysfunction
IMPROVE
infected cells
Infection
Infectious diseases
Inflammation
Inflammatory response
Inflammatory responses
influence
inhibit
innate cytokine
innate cytokines
interferon response
interferons
interferons (IFNs
mechanism
non-infected
pandemic disease
Patient
progression
researcher
respiratory
response
responses
robust
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 protein
SARS-CoV-2 proteins
Science
severe acute respiratory syndrome Coronavirus
severe COVID-19
Shin
South Korea
technology
treatments for COVID-19
triggered
Type
type I
type I and III IFNs
type I and III interferons
type I and type III interferons
Type I IFN
type I IFN responses
type III interferon
viruses
[DOI] 10.1038/s12276-021-00592-0 PMC 바로가기 [Article Type] Review
[DOI] 10.1038/s12276-021-00592-0 PMC 바로가기 [Article Type] Review
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling
중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 막(M) 단백질은 RIG-I/MDA-5 신호전달을 표적으로 하여 I형 및 III형 인터페론 생산을 억제합니다
Article
Published on
Journal: Signal Transduction and Targeted Therapy
[Category] MERS, SARS, 변종, 유전자 메커니즘, 치료법,
Journal: Signal Transduction and Targeted Therapy
[Category] MERS, SARS, 변종, 유전자 메커니즘, 치료법,
[키워드] Activation
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
addition
affected
Antiviral
antiviral immunity
attenuate
caused
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
cytosolic
ectopic expression
ENhance
evade
facilitate
IFN
Immune suppression
individuals
Infection
Infectious diseases
inhibit
Innate immunity
interact
interferon
Interpretation
IRF3
M protein
MAVS
mechanism
membrane
molecular mechanism
multiprotein complex
nuclear translocation
pathogenic
pathway
Phosphorylation
Protein
provide
Replication
reported
respiratory
RIG-I
SARS-CoV-2
SeV
severe acute respiratory syndrome Coronavirus
Signaling
Spread
stimulated
stomatitis
suppresse
suppression
TBK1
the SARS-CoV-2
TRAF3
type I
type I and III IFNs
vesicular stomatitis
vesicular stomatitis virus
Viral
viral replication
[DOI] 10.1038/s41392-020-00438-7 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41392-020-00438-7 PMC 바로가기 [Article Type] Article
Dysregulated Interferon Response Underlying Severe COVID-19
심각한 COVID-19의 기저에 있는 조절되지 않은 인터페론 반응
Review
[키워드] addition
administration
Antiviral
Autoimmunity
autonomous
autoreactive antibodies
autoreactive antibody
coincidence
Comorbidity
COVID-19
COVID-19 pathogenesis
COVID-19 pneumonia
COVID-19 progression
Critical
determine
dysregulation
early stage
elicit
explained
Genetic
high correlation
IFN
IFN response
IFNs
immune
immune interferons
immunopathy
Inborn
individual
Innate
interferon
interferon signaling
interferons
life-threatening
loci
males
mechanisms
Patient
Pneumonia
Prevent
Prophylactic
recent
response
restrict
SARS-CoV-2
SARS-CoV-2 infections
severe COVID-19
severe COVID-19 patient
significantly
situation
spatiotemporal
Therapies
type I
type I and III IFNs
virus infection
worsened
[DOI] 10.3390/v12121433 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/v12121433 PMC 바로가기 [Article Type] Review
Does eNOS derived nitric oxide protect the young from severe COVID-19 complications?
eNOS 유래 산화질소는 심각한 COVID-19 합병증으로부터 젊은이를 보호합니까?
Review
[키워드] activated
Activation
age
Anti-viral
Antiviral
Asian
barrier
bradykinin
Bradykinin (BK)
Cell
change
Complication
complications
COVID-19
COVID-19 mortality
COVID-19 pandemic
COVID-19 patient
COVID-19 patients
death
Decline
decrease
disease
Disease progression
disparity
endothelial
Endothelial cell
endothelial cells
Endothelial cells (ECs)
Endothelial dysfunction
Endothelial nitric oxide synthase (eNOS)
explain
Haplotype
IFN
increased risk
Inflammation
inhibit
Innate immunity
interferon
inverse correlation
lead
mechanism
molecular mechanism
molecular mechanisms
nitric oxide
Nitric oxide (NO).
nitric oxide synthase
NO production
observation
occur
progression
PROTECT
provide
respiratory
SARS-CoV-1
severe COVID-19
severe disease
severe patients
shown
the interferon
the patient
type I
type I and III IFNs
vascular disease
Viral
viruses
Vitamin
Vitamin D
[DOI] 10.1016/j.arr.2020.101201 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.arr.2020.101201 PMC 바로가기 [Article Type] Review